Iranian President Mahmoud Ahmadinejad read out the resolution, which included over seven-hundred clauses, in the final session of the summit on Friday night.
The final communiqué expressed support for Iran's nuclear energy program, rejected the United States' unilateral sanctions against the Islamic Republic, and called for greater efforts to support the Palestinian cause.
The need to combat Islamophobia and racism throughout the world as well as global nuclear disarmament were some of the other key issues mentioned in the document.
In the closing ceremony, President Ahmadinejad hailed the resolution as "effective and historic" and expressed his gratitude to all of the participants of the summit, which he said had a very important message for the entire world.
The draft resolution had been drawn up and approved during the NAM meetings of senior officials and foreign ministers.
Over 100 countries sent representatives to the NAM summit, which kicked off on Sunday with a two-day expert-level meeting in the Iranian capital, followed by a foreign ministerial meeting that ended on Wednesday.
Iran assumed the rotating presidency of NAM for a three-year term on Thursday, when the meeting of heads of state and government opened with an inaugural speech by Leader of the Islamic Revolution Ayatollah Seyyed Ali Khamenei.
NAM is an international organization with 120 member states that is not formally aligned with or against any major power bloc. Nearly two-thirds of the countries of the UN are also NAM members.